Posting Number: req5365
Department: Biomedical Engineering
Location: Main Campus
Address: 1656 E. Mabel St, Tucson, AZ 85721 USA
Position HighlightsThe Tardiff Laboratory in the Biomedical Engineering Department is accepting applications for the position of Research Specialist. The Research Specialist is responsible for maintaining mouse colonies, genotyping, performing basic molecular biology and protein analysis including western blotting, protein expression, and protein purification, etc. In addition, there will also be some lab management responsibilities that will include close work with the Principal Investigator.
The studies in the Tardiff laboratory utilize an integrative physiologic and biophysical approach to delineate the underlying links between structural and functional alterations in cardiac thin filament proteins and the resultant complex cardiovascular phenotypes observed in patients with Hypertrophic Cardiomyopathy (HCM), a disorder affecting 1/500 individuals. Hypertrophic Cardiomyopathy is an autosomal dominant genetic disorder and is one of the most common causes of sudden cardiac death in young people. Work from our lab and others has shown that the molecular effects of independent gene mutations in sarcomeric proteins are varied and disrupt both sarcomeric function and myocellular signaling pathways leading to the complex, often progressive cardiac remodeling that characterizes HCM. While the first gene mutations linked to HCM were published over 20 years ago, many of the basic mechanisms underlying the disorder remain unknown. It is our goal to elucidate these mechanisms by combining techniques from various levels of biological complexity (i.e. computational, in-vitro, and in-vivo).
Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state and optional retirement plans; access to UA recreation and cultural activities; and more!The University of Arizona has been recognized for our innovative work-life programs. For more information about working at the University of Arizona and relocations services, please click here.
Duties & Responsibilities
- Perform administrative functions such as filing, ordering of supplies, maintaining inventory, maintaining databases (for example: mouse colony, chemicals, MSDS, training records, and interface with RLSS).
- Coordinate training of new laboratory members, including ensuring they have performed appropriate online and in person training as well as any appropriate lab tests. Train students and staff in the operation of equipment and/or in the performance of technical procedures.
- Operates laboratory equipment and performs minor equipment maintenance. Communicates with service technicians for major equipment repairs or service.
- Prepare buffers and reagents. Cannulation and ex vivo "hanging" of mouse hearts for adult myocyte isolation (good hand-eye coordination required). Performs basic molecular biology, western blotting, and protein purification.
- Analyze data and draft research progress reports including summarizing test results of assigned project. Assist with data collection and generation of figures for grants.
- Demonstrated ability to effectively communicate and work well with others.
- Strong organizational skills.
- Motivation to expand skill set and take on responsibility for lab management.
- Willingness to acquire new skills, develop new techniques/protocols, and work independently.
- High school diploma or equivalent, or equivalent learning attained through experience required.
- Minimum of 3 years of relevant experience required.
- Some background (coursework) in chemistry required.
- Bachelor degree in a related field
- Prior experience with handling and maintaining mouse breeding colonies, including transgenic mice and inducible mouse models
- Experience with principles and techniques of molecular and cell biology
- Experience with word processing and data presentation skills (e.g. using programs such as Word; Excel; Prism)
Full Time/Part Time: Full Time
Number of Hours Worked per Week: 40
Job FTE: 1.0
Work Calendar: Fiscal
Job Category: Research
Benefits Eligible: Yes - Full Benefits
Rate of Pay: DOE
Compensation Type: hourly rate
Career Stream and Level
Research & Lab
Type of criminal background check required: Name-based criminal background check (non-security sensitive)
Number of Vacancies: 1
Contact Information for Candidates
Professor, Biomedical Engineering
Open Until Filled: Yes
Documents Needed to Apply: Curriculum Vitae (CV) and Cover Letter
At the University of Arizona, we value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community. As an Hispanic-serving institution and a Native American/Alaska Native-serving institution, we translate these values into action by seeking individuals who have experience and expertise working with diverse students, colleagues, and constituencies. Because we seek a workforce with a wide range of perspectives and experiences, we provide equal employment opportunities to applicants and employees without regard to race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity, or genetic information. As an Employer of National Service, we also welcome alumni of AmeriCorps, Peace Corps, and other national service programs and others who will help us advance our Inclusive Excellence initiative aimed at creating a university that values student, staff and faculty engagement in addressing issues of diversity and inclusiveness.